Hepascore
Hepascore is a biochemical severity scoring system based on liver function tests in predicting the extent of liver fibrosis/cirrhosis in patients with hepatitis C infection. Hepascore may also be applicable to other liver diseases and is being trialed for fatty liver disease and hepatitis B infection.
The following markers are analyzed:
- serum bilirubin
- serum gamma glutamyl transferase
- serum alpha 2 macroglobulin
- serum hyaluronic acid levels
These markers along with age and sex are applied to an equation and a score of between 0 and 1.0 is calculated:
- <0.50: significant fibrosis is absent
- ≥0.50: significant fibrosis present
- <0.84: cirrhosis is absent
- ≥0.84: cirrhosis is likely present