Morning glory sign (midbrain)
Imaging
biomarkers in Parkinson’s disease and Parkinsonian syndromes: current and emerging concepts. MRI of a patient with a clinical diagnosis of Progressive Supranuclear Palsy. The image on the left is a sagittal T1 sequence showing the ‘Hummingbird’ sign (box), while the axial T1 sequence on the right shows the ‘Morning Glory’ sign (arrows) both features seen in Progressive Supranuclear Palsy
Morning glory
sign (midbrain) • Progressive supranuclear palsy (PSP) - Ganzer Fall bei Radiopaedia
Morning glory
syndrome (eye) • Morning glory flower - Ganzer Fall bei Radiopaedia
nicht verwechseln mit: Morning glory syndrome (eye)
Morning glory sign of progressive supranuclear palsy (PSP) and multisystem atrophy, refers to the appearance of the midbrain on axial imaging.
Graphically this is identified on an axial image at the level of the midbrain by drawing:
- a horizontal line drawn through the edge of the posterior cerebral aqueduct
- a second line is drawn along the lateral margin of the tegmentum from the intersection of the horizontal line to the "pit" between the tegmentum and the cerebral peduncle
In normal subjects the lateral margin of the tegmentum is convex and runs outside of this second line. However, in patients with progressive supranuclear palsy and multisystem atrophy with vertical supranuclear gaze-palsy the tegmentum is concave and the lateral margin runs inside the second line.
The morphology of the midbrain in patients with vertical supranuclear gaze-palsy resembles the morning glory flower thus termed the morning glory sign as originally described by Adachi et al .
Siehe auch:
Assoziationen und Differentialdiagnosen zu Morning glory Zeichen Mittelhirn: