Okuda staging system

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The Okuda staging system was an advance on earlier hepatocellular (HCC) staging classifications, in that it incorporated both cancer-related variables and liver function related variables to determine prognosis :

  • disease involving >50% of hepatic parenchyma
  • ascites
  • albumin ≤3 mg/dL
  • bilirubin ≥3 mg/dL

These are combined into stages:

  • stage A: 0 criteria
  • stage B: 1-2 criteria
  • stage C: 3-4 criteria

Higher stages were correlated with a poorer prognosis.

History and etymology

The staging classification was published by K Okuda et al in 1985.

See also