peri-ampullary tumours

Periampullary tumors are those that arise within 2 cm of the ampulla of Vater in the duodenum.

Tumors that fall under this group include four main types of tumors  that will be approached in their specific articles:

  • pancreatic head/uncinate process tumors: includes pancreatic ductal adenocarcinoma involving head and uncinate process of the pancreas
  • lower common bile duct tumors: includes types of cholangiocarcinoma involving the intra-pancreatic distal bile duct
  • ampullary tumors: those originating from the ampulla of Vater itself
  • periampullary duodenal carcinoma

Although patients with periampullary tumors have similar symptoms at presentation, they exhibit different clinical outcomes according to the origin of these tumors.

Radiographic features

Their origins are difficult and often impossible to discern based on clinical settings and on preoperative imaging. The presence of a bulging papilla sign may suggest the diagnosis.

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