plasma cell leukemia

Plasma cell leukemia (PCL) is a rare and aggressive form of leukemia and plasma cell dyscrasia. It can be divided into primary (pPCL) and secondary (sPCL) following previously diagnosed multiple myeloma. It is also considered clinically and genetically distinct from multiple myeloma.

Plasma cell leukemia is defined by the observation in blood of more than 20% clonal plasma cells by differential count of the leukocytes or by counting more than 2 × 10 per liter circulating clonal plasma cells.

At time of writing (2020) it is thought to have a fulminant course and poor prognosis.

See also

• WHO classification of tumors of hematopoietic and lymphoid tissues

Siehe auch:

• plasma cell dyscrasia