primary serous papillary carcinoma of the peritoneum

A primary serous papillary carcinoma of the peritoneum (PSPCP) is an extremely rare primary peritoneal tumor.

Epidemiology

They usually present in postmenopausal women.

Clinical presentation

Patients tend to present with non-specific complaints such as abdominal pain, anorexia, and abdominal distention.

Pathology 

It is histologically identical to serous papillary carcinoma of the ovary . PSPCP is believed to originate from either peritoneal mesothelial cells with müllerian differentiation or nests of ovarian tissue remnants within the peritoneum

Markers

Serum CA-125 levels may be elevated .

Radiographic features

CT

While most features are nonspecific, CT features of diffuse peritoneal, omental and mesenterial involvement especially in middle-aged or elderly postmenopausal women with normal-size ovaries in the absence of an identifiable primary site in and conjunction with elevated level of serum CA-125 may suggest the possibility of PSPCP .

Differential diagnosis

On imaging, a PSPCP can resemble that of peritoneal carcinomatosis

Other considerations include

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