pulmonary capillaritis

Pulmonary capillaritis is a general term given to inflammation of the pulmonary capillaries. It is essentially a histopathological diagnosis .

Pathology

The underlying inflammation leads to the disruption alveolar-capillary basement membrane integrity with resultant flooding of the alveoli with blood.

The key histopathologic features of pulmonary capillaritis include

• capillary wall necrosis with infiltration by neutrophils
• interstitial erythrocytes, and/or hemosiderin
• interalveolar septal capillary occlusion by fibrin thrombi

It can result from varying underlying pathology including

• pulmonary vasculitides
• pulmonary infection - pneumonias

If the capillaritis is widespread it can result in diffuse alveolar hemorrhage.

See also

• idiopathic pauci immune pulmonary capillaritis

Siehe auch:

• pulmonale Vaskulitis
• idiopathic, pauci-immune pulmonary capillaritis (IPIPC)

und weiter:

• idiopathic pauci immune pulmonary capillaritis
• pulmonary manifestations of antiphospholipid syndrome