Sanjad Sakati syndrome

Sanjad Sakati syndrome (SSS) is also known as hypoparathyroidism - retardation - dysmorphism (HRD). It is a  rare autosomal recessive genetic disorder.


Exclusively found in people of Arabian origin. There is an equal distribution in both sexes.



Gene of the syndrome is found on chromosome 1q42-q43 .

Clinical presentation

  • hypocalcemic tetany or convulsions
  • mental retardation
  • severe dysmorphic features
  • severe intrauterine and postnatal growth retardation

History and etymology

First definitively described by Sanjad et al in 1991.

Differential diagnosis