sclerosing lobular hyperplasia of breast

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Sclerosing lobular hyperplasia (SLH) of the breast, also known as fibro-adenomatoid mastopathy, is an uncommon benign proliferative breast lesion.

Epidemiology

It tends to occur more often in adolescent and young adult patients (peak age in the thirties). In the United States, there may be a greater incidence in African American women .

Clinical presentation

It often presents as a circumscribed mass and may or may not be palpable.

Pathology

It is histologically characterized by enlarged lobules (with prominent lobular hyperplasia) an increased number of intralobular ductules and sclerosis of the intralobular connective tissue.

Associations

fibroadenoma: a fibroadenoma can have surrounding SLH in ~ 50% of cases

Radiographic features

Mammography

May present as a rounded radiodensity of variable size (1-8 cm ) and may resemble a non-calcified fibroadenoma.

Breast ultrasound

Has a nonspecific sonographic appearance and may be seen as a lobular or oval-shaped mass with a circumscribed margin .

Differential diagnosis

General differential considerations include

non calcified fibroadenoma: also as association
well marginated breast neoplasm