serous carcinoma of the cervix
A papillary serous carcinoma of the cervix (PSCC) is an uncommon histological type of cervical cancer. It is considered a sub type of adenocarcinoma of the cervix.
Epidemiology
Accodring to some studies, there was a bimodal age distribution, with one peak occurring before the age of 40 years and the second peak after the age of 65 .
Pathology
Papillary serous adenocarcinoma of the cervix resembles microscopically its counterparts elsewhere in the female genital tract and peritoneum.
Markers
PSCC may give a significantly higher p53 and lower CEA reactivity than other more common histologic subtypes
Staging
Staging is same other cervical tumors - see - cervical cancer staging
Treatment and prognosis
These tumors can behave aggressively with supradiaphragmatic metastases and a rapidly fatal course when diagnosed at an advanced stage, but the outcome for patients with stage I tumors is similar to that of patients with cervical adenocarcinomas of the usual type .
The following factors have been associated with a poorer prognosis
- age <65 years at diagnosis
- stage > I
- tumor size > 2 cm
- tumor invasion > 10 mm
- presence of lymph node metastases
- elevation of serum CA-125
In contrast to ovarian, tubal, and endometrial serous carcinomas, local therapy appears to be effective treatment for many serous carcinomas of the cervix .
See also
Siehe auch:
- Zervixkarzinom
- WHO histological classification of tumours of the uterine cervix
- Zervixkarzinom Staging
- adenocarcinoma of cervix
und weiter:
Assoziationen und Differentialdiagnosen zu serous adenocarcinoma of cervix:
