talcosis
Pulmonary
talc granulomatosis mimicking malignant disease 30 years after last exposure: a case report. Ill-defined, mass-like density in the right middle lobe of the lung.
Pulmonary
talc granulomatosis mimicking malignant disease 30 years after last exposure: a case report. Spiculated opacity suspicious for lung malignancy. Maximum diameter 4.5 cm.
Talcosis is a type of pneumoconiosis and can be prevalent in intravenous drug users. It is one of the four recognized types of talc-induced lung disease.
Pathology
Talc (magnesium silicate) is used in the preparation of tablets intended for oral use, where it acts as a 'filler' and lubricant. When these tablets are ground down, dissolved and injected for illicit use, the talc accumulates in the pulmonary circulation. These deposits result in small foreign body reaction granulomas, which are birefringent under polarized light. If use is persistent the nodules can coalesce to form larger masses.
Radiographic features
Intrinsically hyperdense micronodules (<1 mm) can be visible on CT.
CT
- ground glass opacities
- hyperdense micronodules (<1 mm )
- conglomerate masses, similar to progressive massive fibrosis of silicosis
- panlobular emphysema thought to be as a result of methylphenidate (Ritalin) use rather than talc
See also
Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu Talkosis:
