Zebra stripe sign (bones)
Osteogenesis
imperfecta • Osteogenesis imperfecta and bisphosphonate lines - Ganzer Fall bei Radiopaedia
Osteogenesis
imperfecta • Osteogenesis imperfecta - Ganzer Fall bei Radiopaedia
Alternating
radiolucent and radiodense metaphyseal lines • Zebra lines - Ganzer Fall bei Radiopaedia
Alternating
radiolucent and radiodense metaphyseal lines • Zebra sign - pamidronate therapy - Ganzer Fall bei Radiopaedia
Osteogenesis
imperfecta • Osteogenesis imperfecta - Ganzer Fall bei Radiopaedia
Osteogenesis
imperfecta • Treated osteogenesis imperfecta (zebra stripe sign) - Ganzer Fall bei Radiopaedia
Zebra stripe
sign (bones) • Zebra stripe sign - Ganzer Fall bei Radiopaedia
Zebra stripe
sign (bones) • Zebra stripe sign - Ganzer Fall bei Radiopaedia
Zebra stripe
sign (bones) • Zebra (photo) - Ganzer Fall bei Radiopaedia
The zebra stripe sign occurs where children with osteogenesis imperfecta have been treated with cyclical bisphosphonate therapy, e.g. pamidronate. When the drug is delivered in cycles, dense bone is formed while treatment is being given. This results in dense stripes across the metaphyses of bones which can be visualized radiographically.
This sign is not to be confused with the zebra sign , which refers to remote cerebellar hemorrhage.
Differential diagnosis
See also
- solitary radiolucent metaphyseal lines
- solitary radiodense metaphyseal lines
- alternating radiolucent and radiodense metaphyseal lines
