primäres Lymphom der Muskulatur
Muscle
lymphoma • Lymphoma with vertebral involvement - Ganzer Fall bei Radiopaedia
Muscle
lymphoma • Psoas muscle lymphoma - Ganzer Fall bei Radiopaedia
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Ultrasound examination of the left lower extremity revealed large poorly defined hypoechoic regions (arrow head) within the muscles of the medial compartment of the thigh (a) and gastrocnemius (b, c). The hypoechoic regions irregularly infiltrated normal muscle tissue, with texture resembling muscle fibers retaining continuity with the surrounding muscles (arrow). The architecture of the adjacent muscles appeared to be preserved. Color and power Doppler ultrasound showed hypervascularity (a, b)
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Sagittal T1-weighted images (a), T2-weighted images with fat suppression (b), and axial T2-weighted images with fat suppression (c) showing diffuse swelling that infiltrated the gastrocnemius (arrow head), a minimally heterogeneous hypointense signal on T1-weighted images, a hyperintense signal on T2-weighted sequences (arrow in a, b), and an ill-defined boundary
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Axial plain (a), intravenous-contrast-enhanced (b), and coronal reconstruction-contrast-enhanced (c) CT scans showing diffuse swelling of the muscles of the medial compartment and posterior compartment of the thigh. Muscles were enlarged and contained patchy hypodense regions, with indistinct margins (arrow head). The vessels enhanced as they normally would and probably appeared more conspicuous as compartmental compression impairs blood flow (arrow in b). Following intravenous contrast administration, there was slightly patchy and mild enhancement of the lesions (b, c)
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Percutaneous US-guided biopsy of the hypoechoic solid-appearing parts of the lesions within the gastrocnemius (arrow)
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Positron emission tomography/computed tomography (PET/CT) showing multiple lesions of increased FDG-uptake in the left obturator externus muscle, the muscles of the medial and posterior compartments of the thigh (a), and the posterior and peroneal muscles of the calf (b). (a1 &b1) CT image showing ill-defined intramuscular lesions. (a3 & b3) PET/CT image showing multiple lesions with FDG uptake (maximum standardized uptake: 10.20). (a2, a4 and b2, b4) FDG images
Imaging
features of skeletal muscle lymphoma: a case report and literature review. Imaging features of skeletal muscle lymphoma
Muscle lymphoma is a rare manifestation of lymphoma.
Epidemiology
Muscle lymphoma is rare, representing <2% of all lymphomas. The average age of presentation is 70 years .
Clinical presentation
Focal swelling and/or pain along with B-type symptoms . Any muscle can be involved but most commonly :
- thigh
- trunk
- upper limb
- leg
Pathology
Muscle lymphoma is typically the non-Hodgkin type. It can manifest in two ways :
- metastatic spread from primary disease (e.g. nodal, osseous)
- primary lesion (i.e. primary muscle lymphoma), which is less common
Risk factors
Radiographic features
MRI
Muscle enlargement with focal mass or diffuse abnormal signal :
- T1: iso- or hyperintense to normal muscle
- T2: intermediate signal intensity to fat and muscle
- Gad (C+): diffuse (more common), thick peripheral and/or septal marginal enhancement
Differential diagnosis
Other soft tissue tumors should be considered :
- metastatic carcinoma
- rhabdomyosarcoma
- extraskeletal Ewing sarcoma
Infection (pyomyositis) should also be considered.
Siehe auch:
Assoziationen und Differentialdiagnosen zu primäres Lymphom der Muskulatur:
