Bethesda criteria of hereditary non-polyposis colorectal cancer

The Bethesda criteria are an alternative to the Amsterdam criteria for the clinical diagnosis of hereditary non-polyposis colorectal cancer (HNPCC).

Diagnosis of HNPCC is made if any of the following criteria are fulfilled:

• Amsterdam criteria are met
• 2 or more HNPCC related malignancies 
• patient with colorectal cancer (CRC) has
  • first-degree relative with CRC or HNPCC related cancer; one of the cancers diagnosed <45 years of age, and the adenoma diagnosed <40 years of age
  • CRC and endometrial cancer <45 years of age
  • right-sided undifferentiated (solid or cribriform) CRC on histology diagnosed <45 years of age
  • signet ring type CRC <45 years of age
  • colonic adenomas <40 years of age

See also

• Bethesda Classification System for thyroid fine needle aspirates

Siehe auch:

• Kolorektales Karzinom
• amsterdam criteria for HNPCC
• hereditary non-polyposis colon cancer syndrome (HNPCC)

und weiter:

• hereditary non-polyposis colorectal cancer