Blueberry muffin syndrome
Blueberry muffin syndrome (a.k.a. blueberry muffin baby or rash) refers to a skin appearance seen in pediatric patients with multiple raised cutaneous, classically blue/purple lesions which is due to extramedullary hematopoiesis in the dermis.
The syndrome was originally described in congenital rubella cases in the United States in the 1960s . It is also seen in other congenital infections, malignancies (e.g. primary adrenal neuroblastoma) and hematological disorders.
congenital vascular disease
- multiple hemangiomas of infancy
- multifocal lymphangioendotheliomatosis
- blue rubber bleb nevus syndrome
- multiple glomangiomas
- Langerhans cell histiocytosis (LCH)
- neonatal lupus erythematosus