Chorea

Chorea is a type of dyskinesia characterized by sudden, rapid, involuntary, and purposeless movements that happen during a person’s normal voluntary movement.

Pathology

It is a clinical symptom related to different etiologies, such as infectious, inflammatory, vascular, hereditary (e.g. Huntington's disease), drug-induced, degenerative, and neoplastic causes .

Despite the fact that the pathophysiology of chorea is not fully understood, it is thought that it is a consequence of dysfunctional neuronal networks interconnecting the basal ganglia and frontal cortical motor areas, where a deficit in inhibitory signals from the basal ganglia lead to extra and unwanted movements .

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