Facial angiofibromas

Facial angiofibroma, also known as fibrous papule, is a fairly common skin lesion seen in males and females after puberty.

Pathology

They represents a focal vascular and collagen growth.

This lesion is usually solitary and located on the nose skin, measuring 1-5 mm.

There is no hereditary predisposition for this skin lesion. However, multiple angiofibromas, which have a bilaterally symmetrical distribution on face, involving the cheeks, nasolabial folds and chin, have been associated with genetic conditions such as:

• tuberous sclerosis
• Birt-Hogg-Dubé syndrome
• multiple endocrine neoplasia type 1

Histological variants

There are several histological variants that include

• hypercellular
• clear cell
• pigmented
• pleomorphic
• inflammatory
• granular cell

Siehe auch:

• Angiofibrom