giant cerebral aneurysm
Giant cerebral aneurysms are ones that measure >25 mm in greatest dimension.
Epidemiology
Giant cerebral aneurysms account for ~5% of all intracranial aneurysms . They occur in the 5-7 decades and are more common in females .
Clinical presentation
Patients can present with symptoms and signs of mass effect or subarachnoid hemorrhage .
Pathology
Most commonly represent saccular cerebral aneurysms but may also be fusiform or serpentine in morphology . They are thought to develop via two pathways :
- internal elastic lamina de novo defect
- enlargement from a smaller aneurysm
Location
Compared to non-giant cerebral aneurysms there is an increased incidence in the posterior circulation (~35%) .
Radiographic features
Appearances will depend on whether the aneurysm is non-thrombosed, or partially or completely thrombosed.
CT
- non-contrast: slightly hyperdense, well-defined round extra-axial masses
- may demonstrate a peripheral calcified rim
Treatment and prognosis
There are a variety of endovascular and open surgical techniques to treat these aneurysms. Endovascular options have a lower morbidity .