Leukemia (testicular manifestations)

Leukemia testicular manifestations, or testicular leukemia, can be seen in patients during and after acute leukemia. The blood-testis barrier limits chemotherapy from reaching the testicle, and therefore the testicle can act as a harbor for leukemic cells.

  • typically presents with painless testicular enlargement
  • ultrasound appearance is often similar to testicular lymphoma, but it can have a very wide range of appearances:
    • testicular enlargement
    • unilateral or bilateral
    • focal or diffuse
    • hypoechoic to hyperechoic
  • given the non-specific imaging features, clinical history is mandatory for a diagnosis

See also