Lissenzephalie

Newborn with

hydrocephalus on prenatal ultrasound. Axial T1 (left) and axial T2 (right) MRI without contrast of the brain shows a decreased number of gyri and sulci resulting in a nearly smooth brain. There is ventriculomegaly. Overall the brain has an hourglass or figure of 8 appearance. The diagnosis was lissencephaly type I classic.

Galloway-Mowat

syndrome in Taiwan: OSGEP mutation and unique clinical phenotype. Images of fetal ultrafast MRI. a Patient III-1 at 34 weeks of gestation shows pachygyria, especially in the bilateral frontal lobes, and poor myelination of the white matter (b) Patient III-2 at 32 weeks of gestation shows hypomelination with T2 hyperintensity in bilateral cerebral white matter, particularly both temporal lobes (arrows), and prominence of retrocerebellar cisterns due to cerebellar atrophy (arrowheads)

Galloway-Mowat

syndrome in Taiwan: OSGEP mutation and unique clinical phenotype. Brain images of the patients. a Non-contrast enhanced axial carnial CT scan of patient II at 2 days of age showed pachygyria involving bilateral cerebral hemispheres. b Axial sections of MRI of patient III-1 at 9 weeks of age showed gyral abnormalities, frontal pachygyria, and deficient myelination. c MRI of patient III-2 at 6 days of age showed pachygyria and hypomyelination with T2 high signal intensity of white matter in bilateral frontal and temporal lobes. d Non-contrast enhanced axial carnial CT scan of patient V at 1 month of age showed pachygyria involving bilateral cerebral hemispheres

Lissencephaly

type I - subcortical band heterotopia spectrum • Type I lissencephaly - Ganzer Fall bei Radiopaedia

Lissencephaly-pachygyria

spectrum • Type I lissencephaly - Ganzer Fall bei Radiopaedia

Lissencephaly

type I - subcortical band heterotopia spectrum • Lissencephaly type I - Ganzer Fall bei Radiopaedia

Lissencephaly-pachygyria

spectrum • Lissencephaly - Ganzer Fall bei Radiopaedia

Lissencephaly-pachygyria

spectrum • Agyria - Ganzer Fall bei Radiopaedia