löfgren syndrome
Löfgren syndrome is a specific acute clinical presentation of systemic sarcoidosis that usually manifests with lymphadenopathy, fevers, erythema nodosum, and polyarticular arthritis.
Terminology
It is important to not confuse this syndrome with Löffler syndrome, as the names are quite similar but the conditions quite different.
Epidemiology
Löfgren syndrome has a strong predominance for females in their thirties .
Clinical presentation
It typically consists of:
- constitutional symptoms
- fever
- malaise
- erythema nodosum
- hilar lymphadenopathy: see thoracic manifestations of sarcoidosis
- arthritis
- symmetrical polyarthropathy
- most commonly affecting the ankles
- see musculoskeletal manifestations of sarcoidosis
- uveitis (occasionally)
- parotitis (occasionally)
Treatment and prognosis
Compared to run-of-the-mill sarcoidosis, patients presenting with Löfgren syndrome typically have a better overall prognosis with a self-limited clinical course (mean ~2 months ) and spontaneous remission.
History and etymology
It was initially described by Sven Halvar Löfgren (1910-1978), a Swedish physician, in 1952 .
Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu löfgren syndrome:
