MALT-Lymphom

Malt lymphoma
of the lacrimal gland in a patient with Sjogren syndrome.. Coronal T2W STIR image depicts the enlarged left lacrimal gland with increased signal (arrow).
www.eurorad.org • CC by-nc-sa-4.0
Primary
hepatic mucosa-associated lymphoid tissue lymphoma: a case report and literature review. Enhanced magnetic resonance imaging after gadolinium injection. The tumor was hyper-intense on T1-weighted images (arrow) in the area adjacent to the main posterior biliary duct in the arterial phase but showed rapid washout in the late phase
surgicalcasereports.springeropen.com • CC-by-4.0
Primary
pulmonary mucosa-associated lymphoid tissue lymphoma with amyloid light chain-type amyloidosis. a–c Chest computed tomography showed multiple nodules in the right S3, right S7, left S1 + 2, and left S8. d Fluorodeoxyglucose-positron emission tomography showed FDG accumulation in pulmonary nodules to the horizontal slice as b
surgicalcasereports.springeropen.com • CC-by-4.0
Primary
pulmonary mucosa-associated lymphoid tissue lymphoma computed tomography findings: a case report. Chest X-ray shows a large consolidation with air bronchograms in the left lung, and a small area of consolidation in the lower region of the right lung.
casesjournal.biomedcentral.com • CC-by-2.0
Primary
pulmonary mucosa-associated lymphoid tissue lymphoma computed tomography findings: a case report. High-resolution CT scans with parenchymal (A and B) and mediastinal (C and D) window settings demonstrate a consolidation with air bronchogram in the apicoposterior segment of the left upper lobe, and in the superior segment of the left lower lobe.
casesjournal.biomedcentral.com • CC-by-2.0
Radiopaedia • CC-by-nc-sa 3.0 • de

Mucosa-associated lymphoid tissue (MALT) lymphoma, also called extranodal marginal zone B-cell lymphoma, is a type of low-grade extranodal lymphoma.

Epidemiology

MALT lymphoma represents ~7.5% of non-Hodgkin lymphomas. The average age of presentation is 60 years with a slight female predominance . Prevalence is estimated at 2 per 100,000 .

Clinical presentation

Clinical presentation depends on the affected organ. B-type symptoms are rare .

Pathology

MALT lymphomas arise in epithelial tissues where lymphoid cells are not usually found. Chronic infection/inflammation has been implicated in the pathogenesis, for example, Helicobacter pylori infection with gastric MALT lymphoma, and Sjögren syndrome with salivary gland MALT lymphoma . Less than 10% transform from low-grade to high-grade disease .

MALT lymphoma can localize throughout the entire body :

Metastases to other sites including lymph nodes and bone marrow are not uncommon.

Radiographic features

Imaging features of MALT lymphoma depend on which organ is affected.

Treatment and prognosis

MALT lymphoma is considered an indolent disease with a good prognosis. Treatment should be tailored to the affected organ and may consist of surgery, chemotherapy, and/or radiation therapy . Antibiotics are used to treat gastric MALT lymphoma; there is a lack of evidence for its use in treating non-gastric MALT lymphoma .

See also

Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu MALT-Lymphom:
orbitales
Lymphom
Wikipedia • CC BY-SA 4.0
bronchus
associated lymphoid tissue lymphoma
jmedicalcasereports.biomedcentral.com • CC-by-2.0