Middle cerebellar peduncle
The middle cerebellar peduncles contain afferent white matter projection fibers which originate in contralateral pontine nuclei. The corticopontocerebellar pathway is the predominant afferent fiber pathway that passes through the MCP. The corticopontocerebellar pathway itself is involved in the communication between the cerebellum and the prefrontal cortex for the coordination and planning of motor tasks.
Diseases affecting the middle cerebellar peduncles present with clinical signs ipsilateral to the MCP lesion. This is a result of the dual decussation of cerebellar pathways .