nodular regenerative hyperplasia

Fatal liver

mass rupture in a common-variable-immunodeficiency patient with probable nodular regenerating hyperplasia. Hepatic imaging A–D. The initial multiphasic CT. A The non-contrasted image shows no abnormal intrahepatic bleeding. B The arterial phase shows multiple poorly-defined, arterial-enhancing nodules scattered throughout both hepatic lobes (white arrows). In portovenous phase C and 5 min-delayed phase D, these nodules remain iso- to hyperattenuating compared to the adjacent liver parenchyma. Hepatic imaging E–F. The 7-month follow-up CT. E The non-contrasted image shows multiple areas of intrahepatic bleeding (black arrowheads) and intraperitoneal bleeding (black arrows). F The portovenous phase demonstrates disruption of the liver capsule (white arrowhead), suggesting rupture of these hypervascular liver lesions