Osteosarkommetastasen

CT findings

of high-attenuation pulmonary abnormalities. Metastatic osteosarcoma. Axial CT shows parenchymal and pleural calcified metastatic lesions in both haemothoraces (arrows)

Tumor lysis

syndrome following ifosfamide monotherapy in metastatic osteosarcoma: a case report and review of the literature. a Anterioposterior (AP) chest X-ray demonstrating innumerable pulmonary nodules and masses consistent with metastatic disease. b AP pelvis X-ray demonstrating pathological fractures involving the right superior and inferior pubic rami, right acetabulum, and pubic symphysis. c Representative coronal MRI cross section demonstrating a large multilobulated, irregular mass involving the right hemipelvis with intraosseous and soft tissue components. The mass demonstrates predominantly low T1 signal and heterogeneous STIR signal measuring (in unshown cross-sections) 15.3 × 21.7 × 12.7 cm. The mass completely replaces the marrow space of the right acetabulum extending into the ilium, pubis involving the pubic symphysis, and ischium with associated pathologic fractures and destruction of the cortex. There is mass effect upon the right iliopsoas musculature with likely invasion. The same process is seen within the left hip rotators and adductors.