primäres Lymphom der Pleura
Primary pleural lymphoma is extremely rare, especially in immunocompetent patients.
Epidemiology
Primary pleural lymphoma accounts for <0.5% of all non-Hodgkin lymphoma and ~2.5% of primary chest wall tumors .
Pathology
Primary pleural lymphoma may be Hodgkin or non-Hodgkin lymphoma with diffuse large B-cell accounting for the majority (60%) of cases .
Etiology
Primary pleural lymphoma has been described in the setting of chronic inflammation or in immunocompromised patients :
- body-cavity (i.e. pleural, pericardial or peritoneal) based in patients with HIV
- associated with tuberculosis pyothorax
Case reports exist of primary pleural lymphoma in immunocompetent patients with other proposed causative factors :
- autoimmune disease: Sjogren's syndrome, rheumatoid arthritis, chronic lymphocytic thyroiditis
- EBV infection
Radiographic features
Primary pleural lymphoma may presents with non-specific features :
- solid pleurally-based nodule
- diffuse pleural thickening
- pleural effusion often associated
Differential diagnosis
Other types of pleural tumors should be considered.
Siehe auch:
Assoziationen und Differentialdiagnosen zu primäres Lymphom der Pleura:
