Primary effusion lymphoma
Tumor and
tumorlike conditions of the pleura and juxtapleural region: review of imaging findings. Diagnosis: primary effusion lymphoma. Technique: contrast-enhanced chest CT. Description: A 41-year-old man with a history of HIV, HHV8, and EBV presented with dyspnea and chest pain. The initial CT examination (a, b) shows a prominent unilateral pleural effusion posterior to the right lung. A combination of imaging and clinical findings was suggestive of primary effusion lymphoma, which was histopathologically confirmed. Follow-up CT after treatment (c, d) shows a small residual right-sided pleural effusion
Primary effusion lymphoma is a rare form of non-Hodgkin lymphoma (diffuse large cell B cell lymphoma) characterized by malignant fluid accumulation in the absence of lymphadenopathy.
Typical sites of accumulation include
- pleural space
- pericardium
- peritoneal space
Associations
- immunodeficiency states such as acquired immunodeficiency syndrome (AIDS)
- infections including human herpes virus 8 (HHV8)
See also
- 2008 WHO classification of tumors of hematopoietic and lymphoid tissues
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