Pulvinar sign (Creutzfeldt-Jakob disease)
The pulvinar sign refers to bilateral FLAIR hyperintensities involving the pulvinar thalamic nuclei. It is classically described in variant Creutzfeldt-Jakob disease. It is also described in other neurological conditions:
- Fabry disease: the hyperintense signal is seen on T1 rather than T2
- bilateral thalamic infarcts
- acute disseminated encephalomyelitis (ADEM)