Raindrop skull

The raindrop skull appearance of calvarial multiple myeloma is the presence of multiple, well-defined lytic lesions (punched out lesions) of various size scattered throughout the skull. This term is applied as an analogy to rain hitting a surface and splashing, where it leaves a random pattern of dark spots.

Occasionally, the term is used synonymous (although inaccurately) with the pepper pot skull appearance of multiple lytic lesions of hyperparathyroidism .

See also