hyperparathyroidism

Rugger-Jersey-Wirbelsäule
bei Hyperparathyreoidismus im seitlichen Röntgenbild des Thorax: Grund- und Deckplatten sind deutlich verdichtet.
Wikipedia • CC BY-SA 4.0
Lost bones:
differential diagnosis of acro-osteolysis seen by the pediatric rheumatologist. Frontal radiograph of the left hand in a 14 year old male patient with hyperparathyroidism demonstrates acro-osteolysis (arrowheads), subperiosteal resorption at the middle phalanges (small arrows), brown tumors (large arrows) and diffuse osteopenia
ped-rheum.biomedcentral.com • CC-by-4.0
Teenager with
seizures and an elevated parathyroid hormone level. Bone windows from an axial CT without contrast of the brain shows salt and pepper lesions diffusely throughout the skull.The diagnosis was primary hyperparathyroidism.
pediatricimaging.org • CC-by-nc-sa 4.0
Brown tumours
(ECR 2016 Case of the Day). Choline PET/CT, coronal sections of the neck, PET window.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). Choline PET/CT, axial sections of the pelvis A. CT window B. fusion window.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). MRI of the lower limb, axial sections; A. T1-weighted image, B. T1-weighted post-contrast image.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). MRI of the lower limb, coronal sections A. T2-weighted fat-saturated image; B. T1-weighted fat-saturated post contrast image.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). CT, axial sections; A and B the lower limb, C and D the lower jaw.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). Radiograph of the lower limb, AP and lateral.
www.eurorad.org • CC by-nc-sa-4.0
Brown tumours
(ECR 2016 Case of the Day). Radiograph of the hand, PA
www.eurorad.org • CC by-nc-sa-4.0
School ager
with renal failure. AP radiograph of the knee shows widening of the distal physis of the femur and the proximal physis of the tibia and fibula and frayed metaphyses in the same areas.The diagnosis was secondary hyperparathyroidism.
pediatricimaging.org • CC-by-nc-sa 4.0
Radiopaedia • CC-by-nc-sa 3.0 • de

Hyperparathyroidism is the effect of excess parathyroid hormone in the body. It can be primary, secondary, or tertiary. There are many characteristic imaging features, predominantly involving the skeletal system.

Clinical presentation

Hyperparathyroidism is supported biochemically by either an elevated serum parathyroid hormone level or an inappropriately normal level in the setting of hypercalcemia.

Epidemiology

Associations

Hyperparathyroidism can occur in the context of the following conditions from parathyroid hyperplasia or less commonly multiple parathyroid adenomas :

Pathology

Increased levels of the parathyroid hormone lead to increased osteoclastic activity. The resultant bone resorption produces cortical thinning (subperiosteal resorption) and osteopenia.

Subtypes

Radiographic features

Findings in secondary (and tertiary) hyperparathyroidism are often associated with the osteosclerosis of renal osteodystrophy and the osteomalacia of vitamin D deficiency:

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