Renale Osteodystrophie

Renal
osteodystrophy: A 57-year-old female with end-stage renal disease which results in prominent subchondral resorption resulting in widening of bilateral sacroiliac joints along the iliac surface on AP view of the pelvis (solid arrows). Soft tissue calcifications adjacent to right greater trochanter (dashed arrows), vascular calcification adjacent to the left femoral head (double dashed arrows), and a right femoral dialysis catheter.

Renal
osteodystrophy: AP view of the pelvis (a) in a 26-year-old female with secondary hyperparathyroidism that results in multiple, circumscribed, and expanded lucent areas compatible with brown tumors. Associated fracture deformity of the right femoral head and generalized demineralization.

The clothes
maketh the sign. Bone scintigram in a 25-year-old man with renal failure and arthralgia. A frontal planar image (a) and magnified view (b) demonstrates expansion of the manubrium and sternum without manubriosternal joint expansion resulting in a necktie appearance. In addition, a prominent calvarium and faint visualization of the kidneys are also supportive of a diagnosis of renal osteodystrophy

Radiological
review of skull lesions. Renal osteodystrophy and osteopenia. Patient 1: Axial (a) and coronal (b) head CT images depict granular de-ossification with a “pepper pot” appearance (thick arrows) and loss of distinction of the inner and outer tables (dashed arrows) in this patient with renal osteodystrophy. Patient 2: Axial (c) and coronal (d) head CT images show demineralisation of the skull (arrowheads) in this patient with osteopenia. Note the relative preservation of the distinction of the inner and outer tables in osteopenia

Renal
osteodystrophy • Renal osteodystrophy - hand - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Brown tumors - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Renal osteodystrophy - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Renal osteodystrophy with widespread soft tissue calcification - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Amyloid arthropathy - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Secondary hyperparathyroidism - Ganzer Fall bei Radiopaedia

Renal
osteodystrophy • Renal osteodystrophy - Ganzer Fall bei Radiopaedia
Renal osteodystrophy (ROD), also known as uremic osteopathy, is a constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed:
- osteomalacia (adults)/rickets (children)
- secondary hyperparathyroidism: abnormal calcium and phosphate metabolism
- bone resorption
- osteosclerosis
- soft tissue and vascular calcifications
- brown tumors
- aluminum intoxication, e.g. if the patient is on dialysis
Radiographic features
Imaging findings are many and varied:
- osteopenia: (often seen early) thinning of cortices and trabeculae
- salt and pepper skull
- demineralization: usually subperiosteal, however, it may also involve joint margins, endosteal, subchondral, subligamentous areas, cortical bone, or trabeculae
- subperiosteal resorption: characteristic subperiosteal resorption may be seen on radial aspects of middle phalanges of index and long fingers
- bone sclerosis
- diffuse bony sclerosis
- rugger jersey spine: sclerosis of the vertebral body endplates
- soft tissue calcification
- amyloid deposition: erosion in and around joint
- insufficiency fractures
- Looser zone
- brown tumors
Differential diagnosis
General imaging differential considerations include
- osteomalacia
- rheumatoid arthritis
- seronegative spondyloarthropathies
- neoplasms: multiple myeloma, metastases; brown tumors can mimic primary malignant tumor of bone; amyloid deposition may mimic PVNS or synovial chondromatosis
- osteomyelitis
- occult marrow abnormalities
Siehe auch:
- synoviale Osteochondromatose
- primärer Hyperparathyreoidismus
- Multiples Myelom
- Pigmentierte villonoduläre Synovialitis
- Osteomalazie
- subperiostale Knochenresorption
- Osteodystrophy
- osteomesopyknosis
- Amyloidarthropathie
- Metastasen
- Ostitis fibrosa cystica
- seronegative Spondyloarthropathie
und weiter:
- diffuse bony sclerosis (mnemonic)
- Riesenzelltumor
- dichte metaphysäre Bänder
- renal osteodystrophy of the skull vault
- generalized increased bone density in paediatrics
- Calciphylaxie
- Superscan Szintigraphie
- Rugger Jersey Spine Osteoporose
- Osteoklastom
- Riesenzelltumor des Knochens
- polyostotic bone lesions in adults
- Gefäßverkalkungen
- diffus hypointenses Knochenmarksignal in T1
- diffuse skelettale Sklerosierung


Pigmentierte
villonoduläre Synovialitis ⤙•⤚ Renale Osteodystrophie
Osteomalazie
⤙•⤚ Renale Osteodystrophie
subperiostale
Knochenresorption ⤙•⤚ Renale Osteodystrophie