Weber syndrome

Weber

syndrome • Weber syndrome - Ganzer Fall bei Radiopaedia

Gaillard F, Weber syndrome. Case study, Radiopaedia.org (Accessed on 23 Jul 2023) https://doi.org/10.53347/rID-2665 • CC by-nc-sa 3.0 (modified)

Weber

syndrome • Weber syndrome - Ganzer Fall bei Radiopaedia

Abdrabou A, Weber syndrome. Case study, Radiopaedia.org (Accessed on 23 Jul 2023) https://doi.org/10.53347/rID-58868 • CC by-nc-sa 3.0 (modified)

Weber

syndrome • Weber syndrome - Ganzer Fall bei Radiopaedia

Haouimi A, Weber syndrome. Case study, Radiopaedia.org (Accessed on 23 Jul 2023) https://doi.org/10.53347/rID-95798 • CC by-nc-sa 3.0 (modified)

Radiopaedia • CC-by-nc-sa 3.0 • de

Weber syndrome is a midbrain stroke syndrome that involves the cerebral peduncle and the ipsilateral fascicles of the oculomotor nerve . Occasionally the substantia nigra can also be involved .

Clinical presentation

ipsilateral CN III palsy
- diplopia
- ptosis
- afferent pupillary defect
contralateral hemiplegia or hemiparesis
- involvement of the corticospinal and/or corticobulbar tracts
contralateral parkinsonian rigidity (only if substantia nigra involved)

Pathology

It is usually caused by an ischemic stroke, typically involving branches of the posterior cerebral artery .

Radiographic features

Imaging may be helpful to connect the neurological symptoms with a single causative lesion.

The imaging appearance of Weber and Benedikt syndromes may be similar, as both result from an insult to the oculomotor nuclear complex , however the latter syndrome also involves the red nucleus in the midbrain tegmentum.