Wilson Mikity syndrome

Premature
newborn with respiratory distress. CXR AP at 1 day of life (above) shows bilateral symmetrical ground glass opacities throughout the lungs which have low lung volumes. CXR AP obtained at 30 days of life (middle) shows prominent bilateral interstitial fibrosis with cystic interstitial changes throughout the lungs which have increased lung volumes. CXR AP obtained at 90 days of life (below) shows faint bilateral interstitial fibrosis with cystic interstitial changes throughout the lungs which have even more increased lung volumes.The diagnosis was Wilson Mikity syndrome.
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Wilson Mikity syndrome (WMS) refers to chronic lung disease in premature infants, characterized by early development of cystic interstitial emphysema (PIE). This is now sometimes considered as part of the spectrum of bronchopulmonary dysplasia.

History and etymology

Almost 51 years ago, Wilson and Mikity illustrated a syndrome in premature infants. It includes chronic pulmonary insufficiency of prematurity (CPIP) .

See also

  • chronic pulmonary insufficiency of prematurity