X-linked Opitz G/BBB syndrome

X-linked Opitz G/BBB syndrome (XLOS) is an x-linked disorder with a spectrum of congenital anomalies. Anomalies that may be seen are:

• facial anomalies 
  • ocular hypertelorism
  • prominent forehead
  • widow's peak
  • broad nasal bridge
  • anteverted nares
  • cleft lip and/or palate
•  laryngotracheoesophageal defects
• genitourinary abnormalities
  • hypospadias
  • cryptorchidism
  • hypoplastic scrotum
  • bifid scrotum
• congenital hearing defects
• imperforate or ectopic anus
• midline brain defects
  • Dandy-Walker malformation
  • agenesis or hypoplasia of corpus callosum and/or cerebellar vermis