Keimzelltumor des Retroperitoneums

Surgical
challenges of excision of retroperitoneal germ cell tumors in children: a single institutional study with literature review. A 16-year-old girl presenting with lower back pain (patient #8 in Table 1). a Axial image: CT after intravenous contrast shows a retroperitoneal mass with internal fat and ossification consistent with a teratoma. There is thrombosis of the IVC (white arrow) and a close relationship with the celiac axis (arrowhead). b Coronal reformatted image demonstrates the relationship with the right renal artery (black arrow)
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Surgical
challenges of excision of retroperitoneal germ cell tumors in children: a single institutional study with literature review. A 1-day-old boy with antenatally detected mass in the abdomen (patient #7 in Table 1). a Axial T2-w image with fat suppression shows a mass with cystic and solid components (arrow) within the mesentery. b Sagittal T1-w image shows the close relationship with the celiac axis and superior mesenteric artery (arrow)
aops.springeropen.com • CC-by-4.0
Surgical
challenges of excision of retroperitoneal germ cell tumors in children: a single institutional study with literature review. An 8-month-old boy presenting with excessive crying (patient #9 in Table 1). MRI was performed to further characterize a mass in the upper abdomen detected with ultrasound. a Axial T1-w with fat suppression after injection of gadolinium contrast shows a tumor (arrow) within the mesentery. b Sagittal T2-w image shows the close relationship with the superior mesenteric artery (arrow). c The sagittal T1-w image illustrates the fatty component (high signal; arrow) diagnostic for a teratoma
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Keimzelltumor des Retroperitoneums

Keimzelltumor Radiopaedia • CC-by-nc-sa 3.0 • de

Germ cell tumors are found widely throughout the body and encompass a wide range of individual tumors.

This article does not deal with any specific body locations. For detailed discussion please refer the articles listed at the end of this page.

Pathology

Germ cell tumors arise from ectopic pluripotent stem cells that failed to migrate from yolk endoderm to the gonad. Because they arise from primitive cells, they have variable neoplastic potential and variable degrees of differentiation into a variety of tissues.

Generally, cystic lesions tend to be benign whereas solid lesions tend to be malignant however the final diagnosis is made histologically.

Germ cell tumors are classified by their histology regardless of their location in the body . Although there are many ways of dividing these tumors, a widely used approach is to divide them into seminoma and non-seminomatous tumors.

See: classification of germ cell tumors

Additionally a number of other entities not usually included under the heading of germ cell tumor can be included for completeness, as they share many similarities.  They include:

Benign (grade 0) tumors have a risk of malignancy despite being indolent initially and require close clinical, serological, and radiological follow-up .  There is also a low incidence of malignant transformation of somatic cells (i.e. non germ cell) within these tumors e.g. carcinoma, sarcoma, leukemia .

Siehe auch:
Assoziationen und Differentialdiagnosen zu Keimzelltumor des Retroperitoneums:
verkalkte
retroperitoneale Tumoren
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