Keimzelltumor
Germ cell tumors are found widely throughout the body and encompass a wide range of individual tumors.
This article does not deal with any specific body locations. For detailed discussion please refer the articles listed at the end of this page.
Pathology
Germ cell tumors arise from ectopic pluripotent stem cells that failed to migrate from yolk endoderm to the gonad. Because they arise from primitive cells, they have variable neoplastic potential and variable degrees of differentiation into a variety of tissues.
Generally, cystic lesions tend to be benign whereas solid lesions tend to be malignant however the final diagnosis is made histologically.
Germ cell tumors are classified by their histology regardless of their location in the body . Although there are many ways of dividing these tumors, a widely used approach is to divide them into seminoma and non-seminomatous tumors.
See: classification of germ cell tumors
- seminoma
- non-seminomatous germ cell tumors (NSGCT)
- embryonal cell carcinoma
- choriocarcinoma
- yolk sac tumor
- teratoma
- mixed germ cell tumor
Additionally a number of other entities not usually included under the heading of germ cell tumor can be included for completeness, as they share many similarities. They include:
- epidermoid cyst: ectoderm only with no epidermal appendages
- dermoid cyst: ectoderm only, but with epidermal appendages
- fetus in fetu / fetiform teratoma
- struma ovarii tumor
Benign (grade 0) tumors have a risk of malignancy despite being indolent initially and require close clinical, serological, and radiological follow-up . There is also a low incidence of malignant transformation of somatic cells (i.e. non germ cell) within these tumors e.g. carcinoma, sarcoma, leukemia .
Siehe auch:
- Atherom
- Teratom des Ovars
- fetus in fetu
- Dermoidzyste
- Teratom
- ovarian dysgerminoma
- Dermoidzyste des Ovars
- Seminom
- Chorionkarzinom
- intracranial embryonal carcinoma
- CNS germinoma
- intracranial choriocarcinoma
- intrakraniale Teratome
- ovarian choriocarcinoma
- pure primary ovarian choriocarcinoma
- classification of germ cell tumours
- mediastinales Teratom
- intrakranielles Germinom
- unreifes Teratom des Ovars
- ovarian germ cell tumours
- endodermal sinus tumour
- struma ovarii tumour
- specialised teratomas of the ovary
- Teratom des Hodens
- ovarian yolk sac tumour
- malignant mixed germ cell tumour of the ovary
- testicular germ cell tumours
- pineal yolk sac tumour
- staging of germ cell tumors
- mediastinale Keimzelltumoren
- nichtseminomatöser Keimzelltumor
und weiter:
- Pinealiszyste
- supraselläre Raumforderungen
- Tumoren der Hypophysenregion
- Tumoren der Pinealisregion
- Hodentumoren
- fetal pericardial teratoma
- Pineozytom
- anterosuperior mediastinal mass (mnemonic)
- Tumoren des vorderen oberen Mediastinums
- Germinom
- testikuläre Mikrolithiasis
- Pineoblastom
- teratoma suprasellar
- germ cell tumours of the ovary
- suprasellar / hypothalamic lesions
- Raumforderungen oberes Mediastinum
- dysgerminoma
- tumours of the sellar region
- Embryonales Karzinom
- non-seminomatous germ cell tumours
- testicular yolk sac tumour
- testicular mixed germ cell tumours
- germ cell tumours (mnemonic)
- testicular endodermal sinus tumour
- Epidermoidzyste der Glandula pinealis
- Keimzelltumor lymphogene Metastasierung
- thoracic teratoma
