Keimzelltumor
Germ cell tumors are found widely throughout the body and encompass a wide range of individual tumors.
This article does not deal with any specific body locations. For detailed discussion please refer the articles listed at the end of this page.
Pathology
Germ cell tumors arise from ectopic pluripotent stem cells that failed to migrate from yolk endoderm to the gonad. Because they arise from primitive cells, they have variable neoplastic potential and variable degrees of differentiation into a variety of tissues.
Generally, cystic lesions tend to be benign whereas solid lesions tend to be malignant however the final diagnosis is made histologically.
Germ cell tumors are classified by their histology regardless of their location in the body . Although there are many ways of dividing these tumors, a widely used approach is to divide them into seminoma and non-seminomatous tumors.
See: classification of germ cell tumors
- seminoma
- non-seminomatous germ cell tumors (NSGCT)
- embryonal cell carcinoma
- choriocarcinoma
- yolk sac tumor
- teratoma
- mixed germ cell tumor
Additionally a number of other entities not usually included under the heading of germ cell tumor can be included for completeness, as they share many similarities. They include:
- epidermoid cyst: ectoderm only with no epidermal appendages
- dermoid cyst: ectoderm only, but with epidermal appendages
- fetus in fetu / fetiform teratoma
- struma ovarii tumor
Benign (grade 0) tumors have a risk of malignancy despite being indolent initially and require close clinical, serological, and radiological follow-up . There is also a low incidence of malignant transformation of somatic cells (i.e. non germ cell) within these tumors e.g. carcinoma, sarcoma, leukemia .
Siehe auch:
- Teratom des Ovars
- Teratom
- Epidermoidzyste
- Dermoidzyste
- Dermoidzyste des Ovars
- Seminom
- Chorionkarzinom
- ovarian dysgerminoma
- CNS germinoma
- intrakraniale Teratome
- intrakranielles Germinom
- mediastinales Teratom
- intracranial choriocarcinoma
- ovarian choriocarcinoma
- unreifes Teratom des Ovars
- pure primary ovarian choriocarcinoma
- Teratom des Hodens
- classification of germ cell tumours
- ovarian germ cell tumours
- struma ovarii tumour
- specialised teratomas of the ovary
- ovarian yolk sac tumour
- malignant mixed germ cell tumour of the ovary
- testicular germ cell tumours
- mediastinale Keimzelltumoren
- staging of germ cell tumors
- Foetus in foeto
- nichtseminomatöser Keimzelltumor
- Dottersacktumor
- Dottersacktumor der Glandula pinealis
- Dottersacktumor des Ovars
- intrakranielles embryonales Karzinom
und weiter:
- Pinealiszyste
- Tumoren der Pinealisregion
- testikuläre Mikrolithiasis
- Hodentumoren
- Germinom
- Tumoren des vorderen oberen Mediastinums
- Pineoblastom
- Pineozytom
- Tumoren der Sellaregion
- anterosuperior mediastinal mass (mnemonic)
- Pituitary MRI (an approach)
- germ cell tumours of the ovary
- teratoma suprasellar
- dysgerminoma
- suprasellar / hypothalamic lesions
- Raumforderungen oberes Mediastinum
- non-seminomatous germ cell tumours
- Embryonales Karzinom
- germ cell tumours (mnemonic)
- testicular yolk sac tumour
- testicular mixed germ cell tumours
- Epidermoidzyste der Glandula pinealis
- Keimzelltumor lymphogene Metastasierung
- maligne Neoplasien des Hodens
- Dottersacktumor des Hodens
- fetales perikardiales Teratom
- maligner Keimzelltumor
- Keimzelltumor des Retroperitoneums
