Teratom

Teratomas are germ cell tumors that arise from ectopic pluripotent stem cells that fail to migrate from yolk sac endoderm to the urogenital ridge during embryogenesis. By definition, they contain elements from all three embryological layers: endoderm, mesoderm and ectoderm although frequently, elements from only two layers are evident.

Pathology

Teratomas range from benign, mature, well-differentiated cystic lesions to immature, poorly differentiated lesions with solid components and malignant transformation.  As a result they can contain a large variety of tissue types including.  On occasion, mature teratomas contain elements that undergo malignant transformation (most commonly squamous components).

• fat
• cystic spaces due to mucous production or other exocrine products
• soft-tissue from any part of the body
• calcification including teeth

Location

They are found in a variety of locations, including:

• ovary: see ovarian teratoma (also known as ovarian dermoid cyst)
• testis: see testicular teratoma
• mediastinum: see mediastinal teratoma
  • account for 27% of all teratomas in adults
  • account for 4-13% of all teratomas in children
• intracranial: see intracranial teratoma
• sacrococcygeal region: see sacrococcygeal teratoma

History and etymology

The word teratoma is derived from the word “teratos” in Greek which means monster.

Siehe auch:

• Teratom des Ovars
• Keimzelltumor
• Steißbeinteratom
• mediastinales Teratom
• intrakraniale Teratome
• Teratom des Hodens

und weiter:

• genitourinary curriculum
• Rathke Zyste
• Tumoren der Hypophysenregion
• Pinealiszyste
• ektope Neurohypophyse
• Tumoren des vorderen oberen Mediastinums
• suprasellar cistern lipoma
• Hypophysenadenom
• Pineoblastom
• Seminom
• Tumoren der hinteren Schädelgrube
• Pineozytom
• Thymuslipom
• caudal dysplasia sequence
• pituitary region mass with intrinsic high T1 signal
• anterosuperior mediastinal mass (mnemonic)
• Krebs
• mediastinale Keimzelltumoren
• Seminom des Hodens
• suprasellar / hypothalamic lesions
• teratoma suprasellar
• classification of germ cell tumours
• germ cell tumour classification
• growing teratoma syndrome
• Teratom der Glandula parotis
• Apoplex der Hypophyse
• nichtseminomatöser Keimzelltumor
• mesenteriales Teratom
• eingeblutete Metastasen
• Teratom der Nase
• Teratom des Pharynx
• Merkspruch Keimzelltumoren
• Germinom des ZNS
• reifes zystisches Teratom
• intrakranieller Keimzelltumor
• intracranial germ cell tumours