Kleinhirnatrophie
![](https://pacs.de/sites/default/files/pictures/thumbs/data.pacs.de/1/1/5/5/7/3/34f553a6277f270694a917056fded5_big_gallery_thumb.jpg)
Diffuse
cerebellar atrophy • Cerebellar atrophy - idiopathic - Ganzer Fall bei Radiopaedia
![](https://pacs.de/sites/default/files/pictures/thumbs/data.pacs.de/1/1/5/5/7/4/ff65d5d6ea336909a41740fb710103_big_gallery_thumb.jpg)
Diffuse
cerebellar atrophy • Phenytoin cerebellar degeneration - Ganzer Fall bei Radiopaedia
![](https://pacs.de/sites/default/files/pictures/thumbs/data.pacs.de/1/1/5/5/7/5/124d5db6f94d7ce7654b69c6c00f00_big_gallery_thumb.jpg)
Diffuse
cerebellar atrophy • Superficial siderosis - Ganzer Fall bei Radiopaedia
![](https://pacs.de/sites/default/files/pictures/thumbs/data.pacs.de/1/1/5/5/7/6/af90c0c7f49e641d09ab7841a44491_big_gallery_thumb.jpg)
Diffuse
cerebellar atrophy • Diffuse cerebellar atrophy - Ganzer Fall bei Radiopaedia
![](https://pacs.de/sites/default/files/pictures/thumbs/data.pacs.de/1/1/5/5/7/7/a6fc92b59656483239578c1f7ecafd99aa6420589c921d64418f47dfa2306c16_big_gallery_thumb.jpg)
Diffuse
cerebellar atrophy • Diffuse cerebellar atrophy - Ganzer Fall bei Radiopaedia
Diffuse atrophy of the cerebellum refers to a progressive and irreversible reduction in cerebellar volume. It is a relatively common finding and found in a wide variety of clinical scenarios.
Terminology
Diffuse cerebellar atrophy can be difficult to distinguish from global cerebellar hypoplasia on a single study and can only be distinguished from the latter by demonstrating or implying (clinically) that there has been progressive change over time .
Pathology
Etiology
Diffuse atrophy can result from a variety of causes:
- normal aging
- drugs
- multiple system atrophy
- hereditary cerebellar ataxias
- chronic temporal lobe epilepsy (independently from phenytoin use)
- cerebellitis
- paraneoplastic cerebellar degeneration
- superficial siderosis
- Fahr disease: atrophy not specific to cerebellum
- cerebrotendinous xanthomatosis
- Marinesco-Sjögrensyndrome
- JC virus granule cell neuronopathy
Differential diagnosis
Siehe auch:
- Mega Cisterna magna
- Morbus Fahr
- Multisystematrophie
- Hirnatrophie
- Kleinhirnhypoplasie
- Alkoholinduzierte ZNS-Veränderungen
- Olivopontozerebelläre Atrophie
- Friedreich-Ataxie
- paraneoplastic cerebellar atrophy
- Cerebrotendinöse Xanthomatose
- Louis-Bar-Syndrom
und weiter:
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