Yunis-Varón syndrome

Yunis Varón syndrome is a rare skeletal dysplasia. It is thought to be autosomal recessive.

Radiographic features

• severe neurologic impairment include small cerebellar vermis and dandy walker malformation
• cleidocranial dysplasia
  • absent clavicles
  • macrocrania
  • diastasis of sutures
• micrognathia
• absent thumbs and distal phalanges of fingers
• hypoplasia of the proximal phalanges
• absence of the distal phalanges of the big toes
• pelvic dysplasia/ fractures and bilateral hip dislocation
• poorly delineated lips
• cryptorchidism
• hypospadias 

Treatment and prognosis

The syndrome is usually fatal in infancy.