Hämangioperizytom

Imaging of
skull vault tumors in adults. Hemangiopericytoma. CT (a), T2WI (b), and post-contrast T1WI (c). Dural-based “mushroom-like” mass (arrows) with brain edema (dashed-arrows), intense homogeneous enhancement, and foci of bone lysis (arrowhead)
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Spinal
metastasis from malignant meningeal intracranial hemangiopericytoma: one-staged percutaneous Onyx™ embolization and resection - a technical innovation. Preoperative T2-weighted axial (A) and contrast enhanced sagittal (B) MRI revealed a mass of the L1 vertebral body, originating from the right vertebral arch, extending extra- and intraspinally with a prominent mass effect to the spinal cord. Super selective catheter angiography of the bilateral spinal arteries Th11 to L2 revealed a major tumour blush from feeders originating from the right-sided TH12 spinal artery (C).
wjso.biomedcentral.com • CC-by-2.0
Hemangiopericytoma
(historical) • Solitary fibrous tumor (hemangiopericytoma) - Ganzer Fall bei Radiopaedia
Gaillard, F. Solitary fibrous tumor (hemangiopericytoma). Case study, Radiopaedia.org. (accessed on 23 Oct 2022) https://doi.org/10.53347/rID-4326 • CC by-nc-sa 3.0 (modified)
Radiopaedia • CC-by-nc-sa 3.0 • de

Hemangiopericytoma is a term formerly used to describe a continuum of mesenchymal tumors with elevated cellularity found throughout the body in soft tissue and bone. After many years of controversy, hemangiopericytomas have been shown to not only share histological features similar to solitary fibrous tumors but also similar genetic alteration: genomic inversion of 12q13 locus resulting in fusion of NAB2 and STAT6 genes, the latter expressed and able to be assessed using immunohistochemistry techniques .

As a result, systemically the term "hemangiopericytoma" is no longer routinely used. In the central nervous system, because the appearances of hemangiopericytomas and solitary fibrous tumors are quite different, the distinction has been somewhat kept; in the most recent WHO classification of CNS tumors (2016 update to 4 edition) meningeal hemangiopericytoma and solitary fibrous tumor of the dura are considered as one entity .

History and etymology

The term was first used by the American pathologists Arthur Purdy Stout and Margaret Ransone Murray in 1942 to describe a soft tissue tumor presumably of pericytic origin, with a monomorphic population of compact polygonal or fusiform cells and a branching stromal vascular pattern with a "staghorn" form.

Siehe auch:
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Assoziationen und Differentialdiagnosen zu Hämangioperizytom:
meningeales
Hämangioperizytom
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meningeale
Tumoren
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meningeale
Neoplasien
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