Homer Wright rosettes

Homer Wright rosettes are differentiated tumor cells grouped around a central region containing neuropil (therefore its association with tumors of neuronal origin).

Pathology

Examples of tumors where these can be seen include:

• medulloblastoma (the presence of Homer Wright rosettes in a posterior fossa tumor is nearly pathognomonic for medulloblastoma)
• primitive neuroectodermal tumors (PNETs)
• olfactory neuroblastoma
• pineoblastoma

History and etymology

Homer Wright rosettes are named after James Homer Wright (1869–1928), Massachusetts (USA), developer of the Wright stain .