Intraventricular metastases
Multiple
intraventricular metastases from lung adenocarcinoma with EGFR G719X mutation: a case report. MRI of brain during different periods of treatment a Contrast-enhanced MRI of brain showed heterogeneously enhancing lesions at the posterior horn of the right lateral ventricle and the IV ventricle, with upper ventricle hydrocephalus and edema of the surrounding parenchyma. T2FLAIR showed slightly higher signal of the masses. b Intraventricular lesions and surrounding area of edema observably shrunk with restored ventricular dilatation after 3-month treatment with afitinib. c Masses in the brain remain stable after 10-month treatment while lesions of lung progressed
Intraventricular metastases are a very rare finding. A few intracranial tumors and some extracranial tumors metastasize to the ventricles. The most common site of intraventricular metastasis is the trigone of the lateral ventricles due to high vascularity of the choroid plexuses. The next most common sites are the 4 and 3 ventricles.
Pathology
Etiology
- renal cell carcinoma - most common primary
- melanoma
- breast carcinoma
- lung carcinoma - overall most common metastasis in the choroid plexus (as it is the most common tumor)
- squamous cell carcinoma of the uterine cervix
- colorectal carcinoma
- papillary thyroid carcinoma
Differential diagnosis
See also
Siehe auch:
Assoziationen und Differentialdiagnosen zu intraventrikuläre Metastasen:
