Leontiasis ossea
Leontiasis ossea is largely a historical term used to describe a number of conditions that result in the affected patient's face resembling that of a lion. Although it is most frequently associated with craniofacial fibrous dysplasia, it has a broader meaning encompassing other lesions that have similar appearance .
The distinction is made between true leontiasis ossea (craniofacial fibrous dysplasia) and other conditions having similar external appearance (mimics), however it would be safe to say that as a term it is no longer of clinical use and should be avoided.
In addition to craniofacial fibrous dysplasia the following conditions may mimic leontiasis ossea:
- Paget disease
- gigantism
- craniosynostosis
- tumors of the paranasal sinuses
- syphilitic osteoperiostitis
- uremia with secondary hyperparathyroidism
History and etymology
The famed Virchow first coined the term leontiasis ossea in 1864 . Rudolf Ludwig Carl Virchow (1821-1902) was a German pathologist and statesman .