Mandibular osteoradionecrosis
Mandibular
osteoradionecrosis • Osteoradionecrosis of mandible with infection - Ganzer Fall bei Radiopaedia
Mandibular
osteoradionecrosis • Mandibular osteoradionecrosis with fracture - Ganzer Fall bei Radiopaedia
Mandibular
osteoradionecrosis • Osteoradionecrosis of the mandible - Ganzer Fall bei Radiopaedia
Mandibular
osteoradionecrosis • Mandibular osteoradionecrosis with pathological fracture - Ganzer Fall bei Radiopaedia
Mandibular
osteoradionecrosis • Mandibular osteoradionecrosis - Ganzer Fall bei Radiopaedia
Mandibular
osteoradionecrosis • Mandibular osteoradionecrosis - Ganzer Fall bei Radiopaedia
Osteoradionecrosis
• Mandibular osteoradionecrosis - Ganzer Fall bei Radiopaedia
Osteoradionecrosis
• Osteoradionecrosis of the mandible - Ganzer Fall bei Radiopaedia
Osteoradionecrosis
• Osteoradionecrosis of the mandible - Ganzer Fall bei Radiopaedia
Mandibular osteoradionecrosis (ORN) is more common after radiation therapy for head and neck malignancies due to the superficial position of the mandible, which exposes it to high radiation. The maxilla can also be involved, but this is less frequent.
Epidemiology
Mandibular ORN may occur in ~20% (5-37%) of patients .
Pathology
Mandibular ORN typically occurs in a patient who has received a dose of >60 Gy . Osteoradionecrosis changes may occur within a year of therapy.
Radiographic features
Features include :
- cortical destruction that is ill-defined resulting in a mixed sclerotic-lucent pattern
- sequestration, especially of the buccal bone
- an absence of soft tissue mass is an important feature to differentiate it from neoplastic recurrence but the presence of soft tissue does not exclude ORN
Treatment and prognosis
Conservative treatment is initially medication only (e.g. pentoxifylline, vitamin E) but more severe cases may require hyperbaric oxygen therapy and/or debridement. Some patients will require resection and reconstruction of the mandible .
Complications
- pathological fractures
- infection
- radiation-induced neoplasia
Differential diagnosis
Siehe auch:
Assoziationen und Differentialdiagnosen zu Osteoradionekrose der Mandibula: