MIBG scan is a scintigraphic study that uses metaiodobenzylguanidine, norepinephrine analog, labeled to iodine-123 or iodine-131. It is indicated in the investigation of pheochromocytoma.

MIBG is positive in:

Some mild uptake can be physiologic in :

  • liver
  • salivary glands
  • urinary bladder 
  • heart
  • gastrointestinal tract
  • adrenal glands
  • brown fat 

Cardiac imaging studies with MIBG labeled to radio-iodine may be useful in the evaluation of cardiac toxicity from chemotherapy.

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