multifocal micronodular pneumocyte hyperplasia (MMPH)
Multifocal micronodular pneumocyte hyperplasia (MMPH) is a rare benign hamartomatous proliferation of type II pneumocytes and is seen in association with tuberous sclerosis (TS). It can occur with or without concurrent lymphangiomyomatosis.
HRCT / Contrast CT Chest
Seen as random faint but relatively well defined small (1-10 mm ) nodular lung parenchymal densities in patients with tuberous sclerosis. These tends to be diffusely scattered throughout the lung in a random distribution with regard to the secondary lobule .
Treatment and prognosis
Unlike lymphangiomyomatosis, MMPH is not progressive and therefore treatment is not required .
History and etymology
It was first described by Popper et.al in 1991 .
General imaging differential considerations include