paraneoplastische Hyperkalzämie
Successful
treatment of paraneoplastic hypercalcemia in a patient with giant condyloma acuminatum: a case report. Extract of pelvis computed tomography scan showing a destructive, polycyclic growing tumor. This is a picture of a computed tomography scan that we made to exclude bone metastasis. It shows the tumor mass, growing from the anal region (below in the picture) to the groin region (above). Furthermore it shows the local destructive grow-pattern.
paraneoplastische Hyperkalzämie
paraneoplastisches Syndrom Radiopaedia • CC-by-nc-sa 3.0 • de
Paraneoplastic syndromes occur secondary to the indirect effects of a malignancy and occur remotely to the primary malignancy. Symptoms are mediated by cytokines, hormones or immune cross-reactivity. These syndromes can cause a diverse range of symptoms and can affect multiple systems.
Epidemiology
Paraneoplastic syndromes occur in up to 15% of patients with cancer .
Pathology
Paraneoplastic syndromes arise most commonly with small cell lung cancer as well as gynecological and hematological malignancies.
Paraneoplastic syndromes can affect multiple systems and have a diverse presentation. Some examples are given below :
- paraneoplastic endocrine syndromes
- paraneoplastic neurological syndromes
- paraneoplastic rheumatological/dermatological syndromes
- acanthosis nigricans
- dermatomyositis
- hypertrophic osteoarthropathy
- leukocytoclastic vasculitis
- paraneoplastic pemphigus
- Sweet syndrome
- pyoderma gangrenosum
- Leser-Trélat sign
- paraneoplastic hematologic syndromes
- miscellaneous paraneoplastic syndromes
History and etymology
Paraneoplastic comes from the Greek words for alongside (para), new (neo) and formation (plasis) .
Siehe auch:
