absence of septum pellucidum

Bilateral
closed lip schizencephaly. Axial FLAIR image shows bilateral clefts filled with CSF (elbow arrow), extending from subarachnoid space along convexity up to atria of both lateral ventricles. The cleft is lined with dysmorphic, thickened gray matter (white arrow).
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Isolated
Agenesis of Septum Pellucidum. Figure 1a: Coronal T2W image showing fusion of both lateral ventricles in their bodies and lower position of the fornix.
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Isolated
Agenesis of Septum Pellucidum. Figure 1b: Sagittal T1W image showing normal corpus callosum and neurohypophysis.
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Isolated
Agenesis of Septum Pellucidum. Figure 1c: Axial T2W image showing fusion of both lateral ventricles in their bodies and more or less normal frontal horns and atria of the lateral ventricles. Rest of both cerebral hemispheres are normal.
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Isolated
Agenesis of Septum Pellucidum. Figure 1d: Axial T2W image showing fusion of both lateral ventricles in their bodies. Rest of both cerebral hemispheres are normal.
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Bilateral
closed lip schizencephaly. Axial FLAIR image of brain shows absent septum pellucidum (red circle).
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Bilateral
closed lip schizencephaly. Coronal T2W image of brain shows cortical thickening with dysplastic cortex along perisylvian fronto-temporal region (yellow arrow). Also note absent septum pellucidum (red circle)
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Bilateral
closed lip schizencephaly. Coronal T2W image shows bilateral symmetrical schizencephalic clefts (blue elbow arrows) lined by dysplastic thickened grey matter (white arrows). Septum pellucidum is absent (red circle).
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Radiopaedia • CC-by-nc-sa 3.0 • de

An absent septum pellucidum may rarely be an isolated finding, or more commonly be seen in association with a variety of conditions.

Epidemiology

The septum pellucidum is partly or entirely absent in 2 or 3 individuals per 100,000 in the general population.

Pathology

An absent septum pellucidum may be developmental or acquired secondary to another pathological process .

Cavum septum pellucidum is always visualized between 18 and 37 weeks and within a biparietal diameter of 44 to 88 mm. Failure to detect the cavum septum pellucidum within this time interval requires further investigation. However, the absence of cavum septum pellucidum on the ultrasound exam prior to 18 weeks or later than 37 weeks is considered a normal finding.

Developmental
Acquired

Radiographic features

Non-visualization of the septum pellucidum with direct communication of the frontal horns. Additionally, the following characteristics may be seen :

  • boxing/squaring off of the frontal horns
  • inferior pointing frontal horns
  • abnormally inferiorly positioned fornix (coronal views)
Siehe auch:
und weiter:
Assoziationen und Differentialdiagnosen zu fehlendes Septum pellucidum:
Septo-optische
Dysplasie
bmcmedgenet.biomedcentral.com • CC-by-4.0
isolierte
Agenesie des Septum pellucidum
www.eurorad.org • CC by-nc-sa-4.0
fenestriertes
Septum pellucidum
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