white matter disorders
White matter
disorders • Transient splenial lesion - Ganzer Fall bei Radiopaedia
White matter diseases are a group of conditions that predominantly or significantly affect the white matter of the brain. They comprise a vast heterogeneous group and have a variety of appearances and presentations. They cause disease by altering the process of normal myelination.
Useful groupings
White matter disease can be broadly grouped into:
- demyelinating disorders
- damage and/or destruction of previously normally myelinated structures
- e.g. multiple sclerosis, ADEM
- dysmyelinating disorders
- abnormal structure and function of myelin, usually secondary to a hereditary disorder
- e.g. leukodystrophies (note, however, that many leukodystrophies have a demyelinating component)
- hypomyelinating disorders
- reduction in the amount of otherwise normal myelin
- e.g. hypomyelination of prematurity
Siehe auch:
- Encephalomyelitis disseminata
- Demyelinisierende Erkrankung
- Leukodystrophie
- myelination
- hypomyelinating disorders
- Akute disseminierte Enzephalomyelitis
- dysmyelinating disease
und weiter:
Assoziationen und Differentialdiagnosen zu white matter disorders: