Esophageal lipoma

Esophageal lipomas (or lipomata) are rare fat-containing esophageal lesions.

Epidemiology

They may account for approximately 0.4% of the benign tumors of the alimentary tract . There may be greater male predilection. The average age of presentation is around 50 years.

Clinical presentation

They are usually small, asymptomatic and incidentally detected. When large (>3 cm), patients may present with symptoms such as dysphagia, regurgitation, odynophagia, epigastralgia or hemorrhage.

Pathology

As with all lipomas, they are composed entirely of mature adipocytes with or without mesenchymal tissue elements. There exists a variety of histological subtypes which include spindle cell lipoma, angiolipoma, myolipoma, fibrolipoma, myxoid lipoma, and the common classic lipoma. Some lesions may be pedunculated.

Location

In terms of location, they most commonly occur in the upper one-third of the thoracic esophagus but can potentially occur anywhere from the pharynx to the distal esophagus.

Radiographic features

Fluoroscopy (barium swallow)

They can appear as smooth intraluminal filling defects. Some may be pedunculated.

CT

CT characteristically demonstrates a homogeneous fat attenuation in typical lesions.

MRI

Follows fat signal with a high T1 weighted intensity that becomes low intensity on fat-suppressed images.

Differential diagnosis

Possible differential considerations include

  • liposarcoma arising from the esophageal region: it can be usually differentiated from liposarcoma which appears as a heterogeneous lesion with internal septations and soft tissue components without fat attenuation.

For atypical lesions consider other esophageal lesions such as

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